Sprained Ankle? Here Is a Dependable Protocol to Fix It in As Short As One Week MDs generally recommend the (R.I.C.E) Rest Ice Compression and Elevation protocol as rehabilitation. This approach doesn't rehab the sprained ankle and results in extended delay to the sufferers normal every day life. In most cases, an injured ankle may heal fully in 4-6 weeks, but cutting edge treatment protocols now have shortened treatment to as short as one week.